The Testicular Hormones AMH, InhB, INSL3, and Testosterone Can Be Independently Deficient in Older Men
نویسندگان
چکیده
منابع مشابه
The Daily Profiles of Circulating AMH and INSL3 in Men are Distinct from the Other Testicular Hormones, Inhibin B and Testosterone
The testes secrete four hormones (anti-Müllerian hormone, insulin-like peptide 3, Inhibin B and testosterone) from two endocrine cell types. It is unknown whether anti-Müllerian hormone and insulin-like peptide 3 levels have a diurnal variation, and if so, whether they covary during the day with testosterone and InhB. Sera were obtained from 13 men at 00:00, 06:00, 09:00, 12:00, 14:00, 17:00 an...
متن کاملRelative levels of the proprotein and cleavage‐activated form of circulating human anti‐Müllerian hormone are sexually dimorphic and variable during the life cycle
Anti-Müllerian hormone (AMH) is a gonadal hormone, which induces aspects of the male phenotype, and influences ovarian follicular recruitment. AMH is synthesized as a proprotein (proAMH), which is incompletely cleaved to the receptor-competent AMHN ,C AMH ELISAs have not distinguished between proAMH and AMHN ,C; consequently, the physiological ranges of circulating proAMH and AMHN ,C are unknow...
متن کاملElderly Men Have Low Levels of Anti-Müllerian Hormone and Inhibin B, but with High Interpersonal Variation: A Cross-Sectional Study of the Sertoli Cell Hormones in 615 Community-Dwelling Men
The Sertoli cells of the testes secrete anti-Müllerian hormone (Müllerian inhibiting Substance, AMH) and inhibin B (InhB). AMH triggers the degeneration of the uterine precursor in male embryos, whereas InhB is part of the gonadal-pituitary axis for the regulation of sperm production in adults. However, both hormones are also putative regulators of homeostasis, and age-related changes in these ...
متن کاملRelationship between testosterone levels and depressive symptoms in older men in Amirkola, Iran
Background: Many studies have been carried out on the relationship between testosterone levels and depression in the elderly. Due to the different results of these studies and the importance of depression in old age, this study seems to be necessary. Methods: This cross- sectional study is a part of the Amirkola Health and Aging Project (AHAP) that involves people aged 60 and above living in A...
متن کاملTestosterone deficiency and replacement in older men.
n engl j med 363;2 nejm.org july 8, 2010 189 for new submissions. We welcome continued input from the user community. Comments can be sent via the “contact us” link at www.icmje.org. The Committee will consider comments received before May 1, 2011, when we prepare the next iteration of the uniform conflict of interest disclosure form. The complexity, subjectivity, and emotionality of conflict d...
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ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2016
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/glw143